The Glass Microelectrode Arrays are a powerful tool to provide a simplified model for cardiac and neuronal network research. Since the cells grow in a monolayer on a glass embedded with microelectrode arrays, therefore it is easy to monitor and manipulate cells with desired stimulating sequences in a defined area. Multiple measurements can be easily achieved over a long period of culturing. More excitedly, the network between cardiac and neuronal electrical activities can be studied in a simple environment.