Song et. al. (2023) developed a flexible, conductive hydrogel inspired by fish swim bladders to repair myocardial infarction. It improves cardiomyocyte growth, reduces cell apoptosis and fibrosis, and shows potential for engineered cardiac patches.

In order to examine the electrical propagation between healthy groups and infarcted myocardium groups, electrical mapping system with a MEA (8×8, 64-channel) was used to acquire and plot epicardial activation maps. The conduction velocity was instantly computed by EMapScope software.

More information: https://pubmed.ncbi.nlm.nih.gov/37303598/

@carmine_3Dheart #cardiotwitter #cardiacpatch #Regeneration #science #microelectrodearray #electrophysiology #Cardiology #opticalmapping #calcium #Langendorff #opticalmapping

Li et. al. (2023) showed Sac/Val (a angiotensin receptor-neprilysin inhibitor) susceptibility to atrial fibrillation by improving atrial remodeling in spontaneously hypertensive rats.

Electrical mapping system with a microelectrode array (8×8) was used to acquire and plot epicardial isochronal activation maps. The data were then computed into activation maps & conduction velocity by EMapScope software.

Optical mapping system was used to measure transmembrane potential and calcium transient. Activation time, conduction velocity, rise time, dispersion, amplitude, APD and CTD were automatically calculated by OMapScope.

More information: https://pubmed.ncbi.nlm.nih.gov/37182595/