You et. al. (2023) showed a spontaneous development of reentry from cellular alternans, arising from a combined actions of restitution properties of action potential duration, conduction velocity of excitation wave and interplay between alternants of action potential and the intracellular calcium handling.

Optical mapping system was used to measure transmembrane potential and calcium transient. Activation maps, APD, conduction velocity were further computed by OMapScope software.

https://pubmed.ncbi.nlm.nih.gov/36863774/

#opticalmapping #Cardiology #Langendorff #arrhythmia #actionpotential #heart #electrophysiology #fibrillation #VF

Zhang et. al. (2023) showed the CeO2-based nanozymes against DIC were mediated by the effect of antioxidant stress and the restoration of GPX4 expression, thereby maintaining mitochondrial homeostasis and function, and restoring mitochondria-dependent ferroptosis.

The electrical mapping system with a microelectrode array (6×6) was used to acquire and plot epicardial isochronal activation maps. The mapping data were then effortlessly computed into e.g. conduction velocity, the inhomogeneity index, and absolute inhomogeneity by EMapScope software.

https://pubmed.ncbi.nlm.nih.gov/36904089/

#cardiotwitter #ElectricalMapping #arrhythmia #mapping #electrophysiology #Cardiology #microelectrodearray #cardiotoxicity #Langendorff #heart #science #research