Liu et. al. (2023) showed that an injectable hydrogels (BASCs and Au@Pt/Alg) can regulate the therapeutic efficacy of stem cells through antioxidant & electrical integration in the MI model.

The electrical mapping system with a multi-electrode array (8×8) was used to acquire and digitize the ventricular epicardial conduction signals which were effortlessly translated into e.g. conduction velocity, and absolute inhomogeneity by EMapScope software.

https://pubs.acs.org/doi/10.1021/acsnano.2c07436

#cardiotwitter #ElectricalMapping #arrhythmia #mapping #electrophysiology #Cardiology #microelectrodearray #cardiotoxicity #Langendorff #AtrialFibrillation #science

Song et. al. (2023) showed that sophoridine manifests as a multiple ion-channel blocker and exerts anti-arrhythmic effects ex vivo and in vivo. Meanwhile, SR has great potential as a leading candidate for the treatment of ventricular tachyarrhythmias due to its low proarrhythmic risk in the hERG inhibition assay and induction of EAD.

The electrical mapping system with a multi-electrode array (8×8) was used to acquire and plot epicardial isochronal activation maps. The activation time was calculated as the point of maximal negative slope of the activation waveform. Finally, conduction velocity was calculated by EMapScope software.

The optical mapping system was used to measure transmembrane potential. Activation maps, APD, conduction velocity were further computed by OMapScope software.

https://www.sciencedirect.com/science/article/pii/S094471132300048X?via%3Dihub

#opticalmapping #calcium #membranepotential #heart #science #research