The electrical mapping system was used to detect changes in left ventricular electrical conduction at 15 minutes and 4 weeks after myocardial infarction (MI). Conduction time (CT), conduction velocity (CV), and inhomogeneity index were analyzed to evaluate the electrical integration ability and intervention effect of the normal group, myocardial infarction surgery group, and therapeutic intervention group. The results indicate that this new therapeutic method has therapeutic potential in improving left ventricular electrical conduction.

(A) Representative electrophysiological images of left ventricular spontaneous conduction at 15 min and 4 weeks after MI with/without treatment (from red to blue: bar graph represents the total time of a heartbeat from the first to the last measurement). (B) Representative images of left ventricular conduction dispersion at 15 min and 4 weeks after MI surgery with/without treatment. (C–E) Quantification of conduction time (C), conduction velocity (D), and conduction dispersion (E) at 15 min post-MI modelling. (F–H) Quantification of conduction time (F), conduction velocity (G), and conduction dispersion (H) at 4 weeks after MI surgery with/without treatment. ns indicates p > .05, *p < .05, **p < .01, ***p < .001.

Clinical and translational medicine (IF 6.8)

https://doi.org/10.1002/ctm2.70250