To explain the electrical coupling treatment of CAHP, cardiac electrophysiology was visualized to analyze the compensatory electrical conduction effects of CAHP in the infarct region. The isolated perfused hearts were fluorescently labeled with CT dye and electrically stimulated at the apex. An optical mapping system recorded the electrical activation time and propagation process over the entire heart.

g.Heatmap of the activation time of calcium transient signals from the apices propagating to different regions of the heart. h, i.Physiological potential amplitude (h) and average conduction velocity (i) in the MI and CAHP groups (n = 5 animals).

Nature Communications (IF15.7)

https://doi.org/10.1038/s41467-023-42008-9