Optical mapping was employed to assess myocardial repolarization refractory periods, determine APD90 prolongation post-MI, and analyze action potential (AP) disparities between infarcted and normal cardiac regions. It also quantified depolarization peak height reduction and fastest depolarization activation time in infarcted zones. Additionally, this technique monitored electrical signal conduction, recorded artificially altered longitudinal conduction velocity (CV), and mapped conduction pathways, revealing that SDF-1α@PUE hydrogel ameliorated electrophysiological abnormalities post-MI.

Advanced Materials( IF26.8)

https://pubmed.ncbi.nlm.nih.gov/37665792/