Electrical Mapping
Customised MEAs: 16 to 256 electrodes
Using multi-site recording electrodes in direct contact with excitable tissues or cells, electrical signals are simultaneously acquired from multiple locations. Dedicated software then processes these signals to generate visual maps and dynamic videos, enabling accurate identification, evaluation, and spatial localization of excitation activity.
Simultaneous recording of atrial and ventricular electrical activity
Activation map of field potential at different sites. The conduction direction is from the red area to the blue area with a conduction time of 5.8 ms.
Activation map of field potential at
different sites
Sequential waveforms of excitation times at different sites
Measurable parameters: excitation frequency, pacemaker site, conduction direction and velocity, conduction dispersion, repolarization dispersion, and QT interval dispersion.
In addition to field potential recording, the system enables synchronous monitoring of ventricular systolic pressure, coronary perfusion pressure, monophasic action potentials, electrocardiograms (ECG), and perfusion temperature, providing comprehensive electrophysiological and functional assessment.
【Advanced Functional Materials】A Vascularized Conductive Elastic Patch for the Repair of Infarcted Myocardium through Functional Vascular Anastomoses and Electrical Integration
Previous studies suggested that conductive ECPs display improved electrical integration with infarcted hearts by detecting CX-43 protein expression in the infarcted region. In this article they measured the ...
【Nature Biomedical Engineering】Injectable and conductive cardiac patches repair infarcted myocardium in rats and minipigs
The electrical mapping was performed on the isolated Langendorff-perfused rat hearts after the patches were implanted onto the infarcted hearts for 4 weeks. These results provide evidence that the conductiv ...
【AcsNano】Injectable Hydrogels Encapsulating Dual-Functional Au@Pt Core–Shell Nanoparticles Regulate Infarcted Microenvironments and Enhance the Therapeutic Efficacy of Stem Cells through Antioxidant and Electrical Integration
The electrical propagation of MI was obtained in different groups by electrical mapping and velocities of electric conduction was calculated. (c) Representative epicardial activation maps located on the bor ...
【Research (Wash D C)】Cardiac-Adaptive Conductive Hydrogel Patch Enabling Construction of Mechanical–Electrical Anisotropic Microenvironment for Heart Repair
Heart cells are prone to apoptosis caused by MI-induced hypoxia, and angiogenesis can reduce MI-caused damage by mitigating hypoxia. Angiogenesis plays an essential role in maintaining cardiac vascularizati ...
【Advanced Functional Materials】A Strongly Robust Chitosan-Based Programmed Control Functional Hydrogel Improved Mitochondrial Function and Pro-Vascularization for Adaptive Repair of Myocardial Infarction
MI resulted in a significant delay in the conduction of electrical signals, whereas hydrogel treatment accelerated electrical signal conduction in the infarcted heart. The electrical mapping system was used ...
【Bioactive Materials】A cigarette filter-derived biomimetic cardiac niche for myocardial infarction repair
Previous studies suggested that conductive CPs could act as a robust tool to improve the electrical integration in the infarcted hearts, which was essential for the MI repair. Here, they directly evaluated ...
【Nature Communications】E-cardiac patch to sense and repair infarcted myocardium
Electrical mapping was performed to probe the electrophysiology reconstruction of the infarcted heart after the patches’ transplantation for 4 weeks. Epicardial electrical mapping, through collecting and an ...
【Cell Reports Medicine】A functional cardiac patch promotes cardiac repair by modulating the CCR2- cardiac-resident macrophage niche and their cell crosstalk
The in vitro experiments demonstrated that as the scaffold, pHH CCP improved the intracellular CX43 expression of CMs, while functional PSL/pIL4@pHH CCP further up-regulated the expression of CX43 between C ...
【Biomaterials】A functional cardiac patch with “gas and ion” dual-effect intervention for reconstructing blood microcirculation in myocardial infarction repair
Synchronized cardiac contractions rely on the conduction of electrophysiological signals. The electrical signals in the infarcted area are blocked upon aggregation of the scar collagen. To further explore t ...
