No significant differences were observed in the parameters examined. Typical ECG recordings before and after transesophageal burst pacing are presented in Figure 1A and 1B.  To evaluate the atrial conduction properties, we performed epicardial multielectrode array mapping in isolated Langendorff-perfused hearts. Figure 1F and Figure 1C in the Data Supplement show representative examples of right atrium activation during sinus rhythm from a sham rat (left) and a SP rat on postoperative day 3 (right). In contrast to the atrial activation patterns in sham rats, the maps from SP rats were characterized by inhomogeneous conduction.

 

 

A typical tracing of ECG and esophageal electrogram during sinus rhythm (A). A typical time course of induced atrial fibrillation (AF) followed by burst pacing (B). ECG showing induced AF after burst pacing and spontaneous AF termination. Mean duration of AF episodes (C) and probability of induced AF (D). The mRNA levels of AF-related proinflammatory cytokines interleukin (IL)-1β, IL-6, transforming growth factor (TGF)-β and tumor necrosis factor (TNF)-α in the atria (E). *P<0.01, †P<0.001 vs sham. Representative examples of spontaneous conduction properties of epicardial activation mapping in sham (left) and sterile pericarditis (SP; right) rats analyzed by multielectrode array (F). aVR indicates rightarm augmented unipolar lead; and Eso, esophagus.

 

Circulation. Arrhythmia and electrophysiology, 9(7), e003396.

Huang, Z., Chen, X. J., Qian, C., Dong, Q., Ding, D., Wu, Q. F., Li, J., Wang, H. F., Li, W. H., Xie, Q., Cheng, X., Zhao, N., Du, Y. M., & Liao, Y. H. (2016).

https://doi.org/10.1161/CIRCEP.115.003396.