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How Cardiac Mapping Can Enhance CiPA?
by Dr Jay Lu What is CiPA? The Comprehensive In Vitro Proarrhythmia Assay (CiPA) initiative is created collectively by an international multidisciplinary team of regulatory, industry, and academic scientists to develop a new paradigm for the cardiac safety evaluation of new drugs that provides a more accurate and comprehensive mechanistic-based assessment ...
An Update on COVID-19 Potential Treatment with HCQ
by Dr Jay Lu Hydroxychloroquine (HCQ) has been touted as a promising and effective treatment for patients with the COVID-19 infection. The drug is often recommended to be used in conjunction with azithromycin, an antibiotic. In this article, we will have a closer look at recent studies on hydroxychloroquine, which may ...
Hydroxychloroquine, to Take or Not to Take? -The risk of COVID-19 potential treatment
By Dr Jay LuCoronavirus, COVID-19, or simply as the infamous pandemic that plagued the world since late 2019, we have all heard about the virus spreading across the globe. But how many of us understand the real statistics and risks behind COVID 19? In this article, we aim to shed ...
Why iPSC Technology is Vital to Cardiac Research
According to the World Health Organization, cardiovascular disease, specifically ischemic heart disease, is the leading cause of death worldwide. Cardiovascular diseases result in an estimated 17.9 million deaths each year, which is about 31% of all deaths worldwide (1). Medical researchers are continually working on ways to reduce those numbers ...
Choosing the best light source for your fluorescence experiment
provided by Scientifica Learning Zone https://www.scientifica.uk.com/learning-zone/choosing-the-best-light-source-for-your-experiment There are a variety of light sources that can be used to illuminate a sample during widefield fluorescence microscopy experiments. Choosing the most suitable one requires evaluating the properties of the light sources and balancing out their pros and cons. Here, we will introduce the three ...
Understanding the cell as an electrical circuit
https://www.scientifica.uk.com/learning-zone/understanding-the-cell-as-an-electrical-circuit Lea Goetz1 and Christian Wilms2 1UCL, London, UK 2Scientifica Ltd, Uckfield, UK Electrophysiologists frequently describe cells as electrical equivalent circuits, i.e. a combination of resistors and capacitances. In the following article, we will look at how resistance and capacitance determine the electrical properties of the cell to understand why this ...