This video demonstrates functional assessment of human iPSC-derived cardiomyocytes using our advanced optical mapping system. By simultaneously recording membrane voltage and calcium transients, the system provides detailed insights into cardiac excitation–contraction coupling and electrophysiological behavior. iPSC-derived cardiomyocytes offer a patient-specific and physiologically relevant model that closely reflects human cardiac function. This approach enables precise evaluation of disease mechanisms, cardiotoxicity risks, and drug efficacy, providing a powerful translational platform for personalized medicine and preclinical research.

#opticalmapping #arrhythmia #heart #Langendorff #drugscreening #cardiotoxicity  #cardiacsafety #ipsc #cardiomyocytes #cardiology #electrophysiology #MappingLab @MappingLab_EP