This video demonstration highlights the use of optical mapping technology for simultaneous visualization of whole-heart action potentials and calcium transients using a dual-camera system. The platform enables high-resolution, synchronized recordings to investigate excitation–contraction coupling, conduction patterns, and arrhythmogenic mechanisms under physiological or pharmacological interventions. As a powerful tool in cardiac electrophysiology, optical mapping provides accurate and reproducible insights into cardiac function, disease modeling, and drug response at the organ level.

#opticalmapping #arrhythmia #heart #Langendorff #drugscreening #cardiotoxicity  #cardiacsafety #regeneration #cardiology #electrophysiology #MappingLab @MappingLab_EP