(A). A Langendorff perfused heart and 32 multi-electrode arrays was placed on the right atria. (B). Layout of 32 multi-electrode arrays.(C). representative examples of right atrium waveforms and activation during sinus rhythm from a sham rat (left) and a SP (sterile pericarditis) rat on postoperative day 3 (right) analysed by multielectrode array. In contrast to the atrial activation patterns in sham rats, the maps from SP rats were characterized by inhomogeneous conduction.


Huang Z, Chen X, Qian C, et al. Signal transducer and activator of transcription 3/microRNA-21 feedback loop contributes to atrial fibrillation by promoting atrial fibrosis in a rat sterile pericarditis model[J]. Circulation: Arrhythmia and Electrophysiology, 2016, 9(7): e003396.